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粗球孢子菌小球体和关节孢子的血清学比较

Serological comparison of spherules and arthrospores of Coccidioides immitis.

作者信息

Landay M E, Wheat R W, Conant N F, Lowe E P

出版信息

J Bacteriol. 1967 Nov;94(5):1400-5. doi: 10.1128/jb.94.5.1400-1405.1967.

DOI:10.1128/jb.94.5.1400-1405.1967
PMID:6057798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC276838/
Abstract

Spherule and arthrospore cellular preparations were sonic-treated and separated into their respective supernatant and sediment components. Complement-fixation tests with antispherule and antiarthrospore pooled rabbit sera revealed that the soluble antigens exhibited more serological activity than the sediment preparations. After autoclaving, an arthrospore cellular antigen exhibited increased activity with either antisera, whereas autoclaved spherules exhibited increased activity only with antispherule serum. Complement-fixation tests with coccicioidin and spherule culture supernatant preparations revealed quantitative or qualitative differences in antigenic determinants between these two morphological phases of Coccidioides immitis.

摘要

对球形体和关节孢子细胞制剂进行超声处理，并分离成各自的上清液和沉淀成分。用抗球形体和抗关节孢子混合兔血清进行补体结合试验表明，可溶性抗原比沉淀制剂表现出更多的血清学活性。高压灭菌后，关节孢子细胞抗原与任何一种抗血清的活性均增加，而高压灭菌的球形体仅与抗球形体血清的活性增加。用球孢子菌素和球形体培养上清液制剂进行补体结合试验，揭示了粗球孢子菌这两个形态阶段之间抗原决定簇的定量或定性差异。

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Serological comparison of spherules and arthrospores of Coccidioides immitis.粗球孢子菌小球体和关节孢子的血清学比较
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引用本文的文献

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Development of vaccines for coccidioidomycosis.球孢子菌病疫苗的研发
Mycopathol Mycol Appl. 1970;41(1):177-85. doi: 10.1007/BF02051493.
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Biochemical challenge of microbial pathogenicity.微生物致病性的生化挑战
Bacteriol Rev. 1968 Sep;32(3):164-84. doi: 10.1128/br.32.3.164-184.1968.
3
Soluble antigens of mycelia and spherules in the in vitro detection of immunity to Coccidioides immitis.用于体外检测对粗球孢子菌免疫力的菌丝体和球形体可溶性抗原。
Infect Immun. 1974 Oct;10(4):700-4. doi: 10.1128/iai.10.4.700-704.1974.
4
Delayed-type hypersensitivity responses to a cell wall fraction of the mycelial phase of Coccidioides immitis.对粗球孢子菌菌丝相细胞壁组分的迟发型超敏反应。
Infect Immun. 1975 Nov;12(5):1093-7. doi: 10.1128/iai.12.5.1093-1097.1975.

本文引用的文献

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Serological tests in the diagnosis and prognosis of coccidioidomycosis.血清学检测在球孢子菌病诊断和预后中的应用
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Polysaccharide of Coccidioides immitis.粗球孢子菌多糖
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IMMUNIZATION AGAINST EXPERIMENTAL LETHAL SIMIAN COCCIDIOIDOMYCOSIS USING WHOLE KILLED ARTHROSPORES AND CELL FRACTION.
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COMPLEMENT-FIXATION TITERS IN EXPERIMENTAL COCCIDIOIDOMYCOSIS IN RABBITS.兔实验性球孢子菌病中的补体结合滴度
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Immunogenic properties of nondisrupted and disrupted spherules of Coccidioides immitis in mice.粗球孢子菌完整和破碎小球体在小鼠体内的免疫原性特性
Sabouraudia. 1963 Feb;2:131-42.
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Purification of the spherule-endospore phase of Coccidioides immitis.粗球孢子菌球形体-内生孢子期的纯化
Sabouraudia. 1961 Jun;1:112-5. doi: 10.1080/00362176285190231.
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The accuracy of serologic methods in diagnosis.血清学方法在诊断中的准确性。
Ann N Y Acad Sci. 1960 Aug 27;89:163-77. doi: 10.1111/j.1749-6632.1960.tb20139.x.
9
Rapid production of complement fixation antigens for systemic mycotic diseases. I. Coccidioidin: influence of media and mechanical agitation on its development.系统性真菌病补体结合抗原的快速制备。I. 球孢子菌素：培养基和机械搅拌对其产生的影响。
J Bacteriol. 1959 Jun;77(6):753-6. doi: 10.1128/jb.77.6.753-756.1959.
10
Studies on the growth of Histoplasma capsulatum. IV. Factors influencing conversion of the mycelial phase to the yeast phase.荚膜组织胞浆菌生长的研究。IV. 影响菌丝相转化为酵母相的因素。
J Bacteriol. 1958 Feb;75(2):167-74. doi: 10.1128/jb.75.2.167-174.1958.