绿猴SA7(C8)腺病毒在组织培养中的转化活性
Transforming activity of green monkey SA7(C8) adenovirus in tissue culture.
作者信息
Altstein A D, Sarycheva O F, Dodonova N N
出版信息
Science. 1967 Dec 15;158(3807):1455-7. doi: 10.1126/science.158.3807.1455.
PMID:6058683
Abstract
Simian SA7 (C8) adenovirus can effect transformation of mouse, rat, and hamster cells in tissue culture. The transforming activity of the virus was more pronounced in culture medium containing 0.1 millimolar CaCl(2), a lower concentration than that usually used. The transformed hamster cells were tumorigenic in hamsters.
摘要
猿猴SA7（C8）腺病毒可在组织培养中使小鼠、大鼠和仓鼠细胞发生转化。在含有0.1毫摩尔氯化钙（CaCl₂）的培养基中，该病毒的转化活性更为明显，氯化钙浓度低于通常使用的浓度。转化后的仓鼠细胞在仓鼠体内具有致瘤性。
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