蛙肌中钠离子移动的化学计量学。
The stoicheiometry of sodium ion movement from frog muscle.
作者信息
Harris E J
出版信息
J Physiol. 1967 Nov;193(2):455-8. doi: 10.1113/jphysiol.1967.sp008370.
Abstract
- Further measurements of the consumption of high energy phosphate during the active extrusion of sodium ions from frog muscle were made in the presence of iodoacetate or dinitrofluorobenzene.2. In the presence of iodoacetate the consumption of ATP for phosphorylation of hexose is appreciable and so a deduction is made from the total ATP consumption during the ion movement.3. In the presence of dinitrofluorobenzene the deamination of adenosine monophosphate makes the changes in adenosine triphosphate and diphosphate unequal so that both substances have to be measured.4. The present results point to the active movement of between 2.5 and 3 sodium ions per high energy phosphate bond split.
摘要
在碘乙酸盐或二硝基氟苯存在的情况下，对蛙肌中钠离子主动转运过程中高能磷酸的消耗进行了进一步测量。
在碘乙酸盐存在的情况下，用于己糖磷酸化的三磷酸腺苷（ATP）消耗相当可观，因此要从离子转运过程中的总ATP消耗中进行扣除。
在二硝基氟苯存在的情况下，一磷酸腺苷（AMP）的脱氨基作用使得三磷酸腺苷（ATP）和二磷酸腺苷（ADP）的变化不相等，因此必须对这两种物质都进行测量。
目前的结果表明，每断裂一个高能磷酸键，有2.5至3个钠离子发生主动转运。
相似文献
1
The stoicheiometry of sodium ion movement from frog muscle.蛙肌中钠离子移动的化学计量学。
J Physiol. 1967 Nov;193(2):455-8. doi: 10.1113/jphysiol.1967.sp008370.
2
Consumption of high-energy phosphates during active sodium and potassium interchange in frog muscle.蛙肌中钠钾主动交换过程中的高能磷酸酯消耗
J Physiol. 1966 Jan;182(1):92-109. doi: 10.1113/jphysiol.1966.sp007811.
3
The break-down of adenosine triphosphate in the contraction cycle of the frog sartorius muscle.青蛙缝匠肌收缩周期中三磷酸腺苷的分解。
J Physiol. 1967 Nov;193(2):343-57. doi: 10.1113/jphysiol.1967.sp008361.
4
Energy coupling to sodium transport in frog skeletal muscle.能量与青蛙骨骼肌中钠转运的耦合
Am J Physiol. 1978 Jul;235(1):C25-34. doi: 10.1152/ajpcell.1978.235.1.C25.
5
Basal energy utilization in mammalian skeletal muscle.哺乳动物骨骼肌的基础能量利用
Proc Soc Exp Biol Med. 1968 Apr;127(4):1228-31. doi: 10.3181/00379727-127-32916.
6
Metabolic cooperative control of electrolyte levels by adenosine triphosphate in the frog muscle.三磷酸腺苷对蛙肌电解质水平的代谢协同控制
Biophys J. 1971 Dec;11(12):973-80. doi: 10.1016/s0006-3495(71)86271-9.
7
[Distribution of intracellular ADP, ATP and orthophosphate in the resting and tetanically stimulated frog musculature by means of a fractionated extraction].[通过分级提取法研究静息和强直刺激的青蛙肌肉组织中细胞内二磷酸腺苷、三磷酸腺苷和正磷酸盐的分布]
Pflugers Arch Gesamte Physiol Menschen Tiere. 1968;300(1):1-22.
8
Energy balance in frog sartorius muscle during an isometric tetanus at 20 degrees C.20摄氏度等长强直收缩期间青蛙缝匠肌的能量平衡
J Physiol. 1973 Aug;232(3):467-83. doi: 10.1113/jphysiol.1973.sp010281.
9
[Metabolism of phosphorus esters in the Rana temporaria sartorius treated with a hypertonic Ringer solution].[用高渗任氏液处理的林蛙缝匠肌中磷酸酯的代谢]
Arch Int Physiol Biochim. 1966 Jun;74(3):374-96. doi: 10.3109/13813456609059918.
10
Energy balance in DNFB-treated and untreated frog muscle.二硝基氟苯处理和未处理的青蛙肌肉中的能量平衡。
J Physiol. 1975 Apr;246(3):737-52. doi: 10.1113/jphysiol.1975.sp010913.
引用本文的文献
1
Membrane current and intracellular sodium changes in a snail neurone during extrusion of injected sodium.注射钠排出过程中蜗牛神经元的膜电流和细胞内钠变化
J Physiol. 1969 Apr;201(2):495-514. doi: 10.1113/jphysiol.1969.sp008769.
2
The sodium-potassium exchange pump. II. Analysis of Na + -loaded frog sartorius muscle.钠钾交换泵。II. 对钠负荷青蛙缝匠肌的分析。
Biophys J. 1971 Aug;11(8):631-47. doi: 10.1016/S0006-3495(71)86243-4.
本文引用的文献
1
2
ACTIVATION OF SKELETAL MUSCLE PHOSPHORYLASE B KINASE BY CA.钙离子对骨骼肌磷酸化酶B激酶的激活作用
Biochemistry. 1964 Aug;3:1033-9. doi: 10.1021/bi00896a004.
3
THE BIOCHEMISTRY OF SODIUM TRANSPORT.钠转运的生物化学
Biol Rev Camb Philos Soc. 1964 May;39:160-93. doi: 10.1111/j.1469-185x.1964.tb00953.x.
4
The chemical and energetic properties of muscles poisoned with fluorodinitrobenzene.被氟二硝基苯毒害的肌肉的化学和能量特性。
J Physiol. 1966 Jun;184(3):751-69. doi: 10.1113/jphysiol.1966.sp007946.
5
Consumption of high-energy phosphates during active sodium and potassium interchange in frog muscle.蛙肌中钠钾主动交换过程中的高能磷酸酯消耗
J Physiol. 1966 Jan;182(1):92-109. doi: 10.1113/jphysiol.1966.sp007811.
6
Changes in phosphate compounds during the development and maintenance of rigor mortis.尸僵发展和维持过程中磷酸盐化合物的变化。
J Biol Chem. 1966 Jun 25;241(12):2918-22.
7
The effect of 2,4-dinitrofluorobenzene on the activity of striated muscle.2,4-二硝基氟苯对横纹肌活性的影响。
J Biol Chem. 1965 Oct;240(10):3996-4001.
Zotero 插件