从灰色链霉菌中分离出的新型抗菌剂（U-24,544）。
New antibacterial agent (U-24,544) isolated from Streptomyces griseus.
作者信息
Herr R R, Reusser F
出版信息
Appl Microbiol. 1967 Sep;15(5):1142-4. doi: 10.1128/am.15.5.1142-1144.1967.
Abstract
Antibiotic U-24,544 is a new agent isolated from the culture broth of a streptomycete strain. The antibiotic inhibits a variety of gram-positive and gram-negative bacteria in vitro, but is ineffective in treatment of experimental bacterial infections in mice. It is fairly cytotoxic in mammalian cell cultures and remarkably nontoxic in mice.
摘要
抗生素U - 24,544是从一种链霉菌菌株的培养液中分离出的一种新制剂。该抗生素在体外能抑制多种革兰氏阳性菌和革兰氏阴性菌，但对小鼠实验性细菌感染的治疗无效。它在哺乳动物细胞培养中具有相当的细胞毒性，而在小鼠中则明显无毒。
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