Relier J P, de Gamarra E
Pediatrie. 1984 Jul-Aug;39(5):379-83.
The increase of the fibrinogen level appears to be an important feature in the neonatal infection as well for diagnosis as for prognosis. Levels above 3,50 g per liter during the first days after birth is in favor of bacterial materno-foetal infection and will return to normal in the next 3 days after antibiotics therapy. Conversely high fibrinogen levels persist as long as the infection remains active and must be an indication to modify antibiotics prescription even when bacteriological results are not known.
纤维蛋白原水平的升高似乎是新生儿感染中一个重要特征，无论是对于诊断还是预后。出生后最初几天纤维蛋白原水平高于每升3.50克有利于诊断母婴细菌感染，且在抗生素治疗后的接下来3天会恢复正常。相反，只要感染仍活跃，纤维蛋白原水平就会持续升高，即使细菌学结果未知，这也必定是调整抗生素处方的一个指征。
