Lundborg G, Eiken O, Rank F
Handchirurgie. 1977;9(3):107-11.
The mechanism of tendon healing and the role played by the synovial sheath are still obscure and controversial. In the present experimental study free tendon grafts were nourished by synovial fluid only. By morphological and cytochemical techniques viable cells were found in the superficial zones of the tendon, capable of both proliferation and production and production of new collagen. This repair process affected predominantly the ends of the grafts. At the centre of the specimens degenerative changes appeared to an increasing extent throughout the observation period of 12 weeks. Adhesions to the surrounding tissues did not form. It is concluded that fibroblasts, most probably originated from the superficial cell layers of the tendon are capable of regeneration and synthesis of new collagen and that synovial fluid plays an important role in the metabolic exchange of the superficial scantily vascularized areas of the tendon. The observations are discussed in relation to the present concepts of tendon surgery.
肌腱愈合的机制以及滑膜鞘所起的作用仍然不清楚且存在争议。在本实验研究中，游离肌腱移植物仅由滑液滋养。通过形态学和细胞化学技术，在肌腱的浅表区域发现了有活力的细胞，这些细胞能够增殖并产生新的胶原蛋白。这种修复过程主要影响移植物的末端。在12周的观察期内，标本中心的退行性变化程度不断增加。未形成与周围组织的粘连。得出的结论是，成纤维细胞很可能起源于肌腱的浅表细胞层，能够再生并合成新的胶原蛋白，并且滑液在肌腱浅表血管稀少区域的代谢交换中起重要作用。结合当前的肌腱外科概念对这些观察结果进行了讨论。
