用人类逆转录病毒成人T细胞白血病病毒对食蟹猴进行实验性感染。
Experimental infection of cynomolgus monkeys with a human retrovirus, adult T-cell leukemia virus.
作者信息
Yamamoto N, Hayami M, Komuro A, Schneider J, Hunsmann G, Okada M, Hinuma Y
出版信息
Med Microbiol Immunol. 1984;173(1):57-64. doi: 10.1007/BF02123570.
The experimental infection of six cynomolgus monkeys with adult T-cell leukemia virus (ATLV) was attempted. Three animals were inoculated with living MT-2 cells and three with cell-free ATLV. All animals developed an antibody response to virus-specific glycopolypeptides and viral core polypeptides. ATLV-specific antigens appeared in peripheral lymphocytes from all six animals. Virus expression persisted in all animals. Up to 40 weeks after inoculation no animal developed any symptom of leukemia.
尝试用成人T细胞白血病病毒（ATLV）对6只食蟹猴进行实验性感染。三只动物接种活的MT - 2细胞，三只接种无细胞ATLV。所有动物均对病毒特异性糖多肽和病毒核心多肽产生抗体反应。ATLV特异性抗原出现在所有6只动物的外周淋巴细胞中。病毒表达在所有动物中持续存在。接种后长达40周，没有动物出现任何白血病症状。
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