Herak J N, Pifat G, Brnjas-Kraljević J, Knipping G, Jürgens G
Biosci Rep. 1984 Jul;4(7):559-64. doi: 10.1007/BF01121912.
It has been found that the capacity of lipoproteins for binding Mn(II) ions is dependent on the arrangement of the lipoprotein core. A change in the molecular organization of the LDL core (thermotropic transition) is associated with the change on the lipoprotein surface. In HDL there is no thermotropic transition and no abrupt change of the binding capacity. The observed surface-core correlation might be an important link in understanding how dietary fat influences the lipoprotein metabolism.
已发现脂蛋白结合锰（II）离子的能力取决于脂蛋白核心的排列。低密度脂蛋白（LDL）核心分子组织的变化（热致转变）与脂蛋白表面的变化相关。在高密度脂蛋白（HDL）中不存在热致转变，结合能力也没有突然变化。观察到的表面 - 核心相关性可能是理解膳食脂肪如何影响脂蛋白代谢的重要环节。
