Ng T B, Ho W K, Tam P P
Int J Pept Protein Res. 1984 Aug;24(2):141-6. doi: 10.1111/j.1399-3011.1984.tb00939.x.
beta-Endorphin-like immunoreactivity in whole brains of Sprague-Dawley rat fetuses of different gestational ages was measured by radioimmunoassay and found to increase throughout the gestational period studied. The immunoreactivity in various brain parts (forebrain, midbrain, hindbrain, hypothalamus and pituitary) of late prenatal, early postnatal, young mature and retired breeder rats was also determined. In all the brain parts studied, a maximum in the content and concentration of beta-endorphin-like immunoreactivity was attained when the rats were about 3-4 months old.
通过放射免疫分析法测定不同胎龄的斯普拉格-道利大鼠胎儿全脑中β-内啡肽样免疫反应性，发现其在所研究的妊娠期内不断增加。还测定了产前晚期、产后早期、年轻成年和老龄繁殖期大鼠不同脑区（前脑、中脑、后脑、下丘脑和垂体）的免疫反应性。在所有研究的脑区中，大鼠约3-4月龄时β-内啡肽样免疫反应性的含量和浓度达到最高值。
