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大鼠肌球蛋白轻链2基因的核苷酸序列。

The nucleotide sequence of a rat myosin light chain 2 gene.

作者信息

Nudel U, Calvo J M, Shani M, Levy Z

出版信息

Nucleic Acids Res. 1984 Sep 25;12(18):7175-86. doi: 10.1093/nar/12.18.7175.

Abstract

A rat myosin light chain 2 gene was characterized by nucleotide sequence and S1 mapping analyses. It contains seven exons separated by six introns. The corresponding mRNA is predicted to be 654 nucleotides long (excluding polyA sequences), with 5'-nontranslated, coding, and 3'-nontranslated lengths of 56, 510, and 88 nucleotides, respectively. The predicted amino acid sequence is identical to that from rabbit except that the rat sequence lacks one of two Gly residues located at positions 12 and 13 in the rabbit sequence. From the nucleotide sequence, nascent rat myosin light chain 2 is predicted to have Met Ala preceding Pro at the N-terminal end.

摘要

通过核苷酸序列和S1图谱分析对大鼠肌球蛋白轻链2基因进行了表征。它包含7个外显子,由6个内含子分隔。预测相应的mRNA长度为654个核苷酸(不包括聚腺苷酸序列),5'-非翻译区、编码区和3'-非翻译区的长度分别为56、510和88个核苷酸。预测的氨基酸序列与兔的氨基酸序列相同,只是大鼠序列在兔序列中位于第12和13位的两个甘氨酸残基中缺少一个。根据核苷酸序列,预测新生大鼠肌球蛋白轻链2在N末端的脯氨酸之前有甲硫氨酸-丙氨酸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5cc/320149/9b42a2b0eab1/nar00336-0264-a.jpg

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