长期噪声或每日限水对雄性大鼠垂体-肾上腺轴的影响。
Effects of chronic noise or daily water restriction on the pituitary-adrenal axis in male rats.
作者信息
Armario A, Castellanos J M, Balasch J
出版信息
Rev Esp Fisiol. 1984 Jun;40(2):153-7.
Pituitary-adrenal function was studied in male rats chronically stressed with noise as well as under water restriction regimen. Chronic noise did not modify either in vivo or in vitro corticoadrenal function. Daily water restriction decreased body weight and increased relative adrenal weight as well as the serum levels of ACTH and corticosterone. In vitro corticoadrenal responsiveness to ACTH was similar in control and water restricted rats. Thus, no evidence for increased adrenal sensitivity to ACTH in the pre-watering period was found in water restricted rats.
研究了慢性应激状态下的雄性大鼠的垂体-肾上腺功能，这些大鼠长期处于噪声环境中以及接受限水方案。慢性噪声并未改变体内或体外的肾上腺皮质功能。每日限水会降低体重，并增加肾上腺相对重量以及促肾上腺皮质激素（ACTH）和皮质酮的血清水平。在体外，对照大鼠和限水大鼠的肾上腺皮质对ACTH的反应性相似。因此，在限水大鼠的预给水期未发现肾上腺对ACTH敏感性增加的证据。
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