庆大霉素联合青霉素G、万古霉素或头孢噻肟对G群链球菌的体外杀菌协同作用。
In vitro bactericidal synergy of gentamicin combined with penicillin G, vancomycin, or cefotaxime against group G streptococci.
作者信息
Lam K, Bayer A S
出版信息
Antimicrob Agents Chemother. 1984 Aug;26(2):260-2. doi: 10.1128/AAC.26.2.260.
Abstract
The in vitro bactericidal interactions of penicillin G, cefotaxime, or vancomycin in combination with gentamicin were compared against 20 group G streptococci by the timed kill curve method. Synergy was noted at the following frequencies: penicillin plus gentamicin, 80%; cefotaxime plus gentamicin, 85%; vancomycin plus gentamicin, 90%. There was no bactericidal antagonism observed.
摘要
采用定时杀菌曲线法，比较了青霉素G、头孢噻肟或万古霉素与庆大霉素联合应用对20株G群链球菌的体外杀菌相互作用。协同作用出现的频率如下：青霉素加庆大霉素为80%；头孢噻肟加庆大霉素为85%；万古霉素加庆大霉素为90%。未观察到杀菌拮抗作用。
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