肾素-血管紧张素系统的细胞生物学
Cellular biology of the renin-angiotensin systems.
作者信息
Re R N
出版信息
Arch Intern Med. 1984 Oct;144(10):2037-41.
PMID:6091580
Abstract
The renin-angiotensin system is a major determinant of arterial pressure and intravascular volume in human beings. Recent evidence, however, suggests that renin can be synthesized at local tissue sites and that these local renin-angiotensin systems subserve important physiologic functions. In addition, it appears that there exist intracellular renin-angiotensin "systems" capable of generating angiotensin II intracellularly.
摘要
肾素-血管紧张素系统是人体动脉血压和血管内容量的主要决定因素。然而，最近的证据表明，肾素可在局部组织部位合成，且这些局部肾素-血管紧张素系统具有重要的生理功能。此外，似乎存在能够在细胞内生成血管紧张素II的细胞内肾素-血管紧张素“系统”。
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