Witter R L, Glass S E
Avian Dis. 1984 Jul-Sep;28(3):742-50.
Reticuloendotheliosis virus (REV) was isolated at 21 weeks from a flock of breeder turkeys with lymphoid neoplasms. Except for about 2% mortality due to tumors mainly between 20 and 30 weeks of age, the livability and egg production of the flock were normal. Egg transmission as a source of infection seemed unlikely, because no REV antibodies or production problems were observed in two sister flocks (hatchmates) and in three progeny flocks, and because eggs obtained from the breeder flock at 45 weeks lacked REV group-specific antigen and produced poults negative for REV infection. The virus isolate, designated REV strain 339, produced an acute neoplastic disease when inoculated into young chickens.
网状内皮组织增殖病病毒（REV）于21周龄时从一群患有淋巴样肿瘤的种火鸡中分离出来。除了主要在20至30周龄期间因肿瘤导致约2%的死亡率外，该鸡群的存活率和产蛋量均正常。种蛋传播作为感染源似乎不太可能，因为在两个姐妹鸡群（同孵出的雏鸡）和三个后代鸡群中未观察到REV抗体或生产问题，并且因为在45周龄时从种鸡群获得的种蛋缺乏REV群特异性抗原，所孵出的雏鸡REV感染呈阴性。分离出的病毒被命名为REV 339株，接种到幼鸡中会引发急性肿瘤性疾病。
