Chiou S S, Obata H, Takasaki T, Fukushima Y, Motoike Y, Okuda H, Tanaka S, Kurihara T, Tomimatsu M, Kobayashi S
Gastroenterol Jpn. 1984 Aug;19(4):344-50. doi: 10.1007/BF02779124.
A survey of 2985 apparently healthy Taiwanese in southern Taiwan revealed a high prevalence (18.2%) of hepatitis B surface antigen (HBsAg). It was significantly higher in males (22.3%) than in females (13.6%), but no correlation with family origin, socioeconomic status or residence was established. About one-third of the breeding female HBsAg carriers were HBeAg-positive, and these may be an important source in the spread of HBV. Subtyping of HBsAg in 63 subjects showed adw to be dominant in this area, and 8 subjects with suspicious results had overlapping heterotypic HBV's (7 adwr and 1 adyw) in addition to 2 subjects in which coexistence of HBsAg and anti-HBs was recognized. The association between HBsAg positivity and serum transaminase elevation was significant, especially in the older groups who had a higher abnormal rate. Hepatitis A virus infection was serious too, with nearly 100% of people above 20 years of age being anti-HA antibody positive.
对台湾南部2985名表面上健康的台湾人进行的一项调查显示，乙肝表面抗原（HBsAg）的流行率很高（18.2%）。男性（22.3%）的流行率显著高于女性（13.6%），但未发现与祖籍、社会经济地位或居住地存在关联。约三分之一的育龄期女性HBsAg携带者HBeAg呈阳性，这些可能是乙肝病毒传播的重要源头。对63名受试者的HBsAg进行亚型分型显示，adw在该地区占主导地位，8名结果可疑的受试者除了2名被确认同时存在HBsAg和抗-HBs的受试者外，还有重叠的异型乙肝病毒（7例adwr和1例adyw）。HBsAg阳性与血清转氨酶升高之间的关联显著，尤其是在异常率较高的老年组中。甲型肝炎病毒感染也很严重，20岁以上人群中近100%抗-HA抗体呈阳性。
