Mertens T, Tondorf G, Siebolds M, Kruppenbacher J P, Shrestha S M, Mauff G, Gürtler L, Eggers H J
Institut für Virologie, Universität zu Köln.
Infection. 1989 Jan-Feb;17(1):4-7. doi: 10.1007/BF01643488.
401 sera from patients of a rural hospital in Zimbabwe (1987), 211 South African sera (1982/83), as well as 460 sera from four Katmandu hospitals (1985) were tested for HIV-1 antibodies. The sera from Zimbabwe and Nepal were additionally tested for anti-HIV-2 using a panel of different tests, for hepatitis B markers, and partially for antibodies against other viral, bacterial, and protozoal antigens. Detailed clinical and sociodemographic data were taken from the Zimbabwe and Katmandu patients. The prevalence of HIV-1 antibodies in the Zimbabwe study population was 3.2%. All infections were found in the age group 17 to 30 years (n = 254). The epidemiological situation was entirely different from that of HBV (hepatitis B virus). No serum could be confirmed to be anti-HIV-2-positive, but a definite diagnosis is still difficult to establish. Regular town contacts may be considered a possible risk factor. Antibodies against HIV-1 could not be detected in the South African and Asian sera. The seropositivity for anti-HBc in Katmandu (14%) and the prevalence of HBsAg (1.1%) was much lower than reported from other Asian countries.
对来自津巴布韦一家乡村医院患者的401份血清（1987年）、211份南非血清（1982/1983年）以及来自加德满都四家医院的460份血清（1985年）进行了HIV-1抗体检测。此外，使用一组不同的检测方法对来自津巴布韦和尼泊尔的血清进行了抗HIV-2检测、乙肝标志物检测，并部分检测了针对其他病毒、细菌和原生动物抗原的抗体。从津巴布韦和加德满都的患者那里获取了详细的临床和社会人口统计学数据。在津巴布韦的研究人群中，HIV-1抗体的流行率为3.2%。所有感染均发生在17至30岁年龄组（n = 254）。其流行病学情况与乙肝病毒（HBV）完全不同。没有血清被确认为抗HIV-2阳性，但仍难以做出明确诊断。经常与城镇接触可能被视为一个潜在风险因素。在南非和亚洲血清中未检测到抗HIV-1抗体。加德满都抗-HBc的血清阳性率（14%）和HBsAg的流行率（1.1%）远低于其他亚洲国家的报告水平。
