禽癌病毒MH2的3'末端区域与禽肉瘤病毒Y73和SR-A具有共同的序列元件。
3'-Terminal region of avian carcinoma virus MH2 shares sequence elements with avian sarcoma viruses Y73 and SR-A.
作者信息
Sutrave P, Jansen H W, Bister K, Rapp U R
出版信息
J Virol. 1984 Nov;52(2):703-5. doi: 10.1128/JVI.52.2.703-705.1984.
Abstract
We determined the nucleotide sequence of the acute transforming avian retrovirus MH2 from an HgiAI site within the coding region of its oncogene, v-myc, to the KpnI site within the long terminal repeat. Comparison with published sequences from other retroviruses allowed us to identify all sequence elements in this region. We conclude that MH2 contains a unique assembly of 3'-terminal sequences, which includes part of the helper virus-derived SPC region of avian sarcoma virus Y73 and the complete F3 and F1 segments of Rous sarcoma virus strain SR-A.
摘要
我们测定了急性转化性禽逆转录病毒MH2从其癌基因v-myc编码区内的HgiAI位点到长末端重复序列内KpnI位点的核苷酸序列。与其他逆转录病毒已发表的序列进行比较，使我们能够识别该区域内的所有序列元件。我们得出结论，MH2包含一个独特的3'末端序列组合，其中包括禽肉瘤病毒Y73的辅助病毒衍生SPC区域的一部分以及劳氏肉瘤病毒SR-A株的完整F3和F1片段。
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本文引用的文献
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Molecular cloning of the avian acute transforming retrovirus MH2 reveals a novel cell-derived sequence (v-mil) in addition to the myc oncogene.禽类急性转化逆转录病毒 MH2 的分子克隆揭示了除 myc 癌基因以外的一种新的细胞来源序列（v-mil）。
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Avian carcinoma virus MH2 contains a transformation-specific sequence, mht, and shares the myc sequence with MC29, CMII, and OK10 viruses.禽癌病毒MH2含有一个转化特异性序列mht，并与MC29、CMII和OK10病毒共享myc序列。
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