Engeset A, Sokolowski J, Olszewski W L
Lymphology. 1977 Dec;10(4):198-203.
The output of lymphocytes, monocytes, granulocytes and erythrocytes in peripheral leg lymph from healthy volunteers has been followed during night and everyday activity, during and after venous stasis, ergometer cycling and warm foot bath and during immobilisation in horizontal position over two 24-hour periods. The output of lymphocytes exceeded the output of monocytes and erythrocytes. Granulocytes were not found except immediately after cannulation. The cell output was low during night rest and the horizontal position for 24 hours. After assumption of the upright position the output of lymphocytes increased about 80 times and the output of erythrocytes 40 times probably because of washout of cells accumulated in tissue during rest. During ergometer cycling and venous stasis the output of cells increased and even more in the one hour rest period following this experiment. During venous stasis the output dropped but increased after the stasis had been released. The pattern of variation in lymphocyte, erythrocyte and monocyte output was the same. This indicate that the fluctuation in output depends on variation in blood flow in the tissue. The output of cells during and after heating seems to be dependent also on increased capillary permeability for cells as the output of erythrocytes exceeded the output of lymphocytes. The high erythrocyte/lymphocyte ratio in blood versus a low ratio in lymph shows that these two cell types pass through the capillary wall by different mechanisms.
在两个24小时时间段内，对健康志愿者腿部外周淋巴液中淋巴细胞、单核细胞、粒细胞和红细胞的输出情况进行了跟踪观察，观察时段包括夜间和日常活动期间、静脉淤滞期间及之后、测力计骑行和热水足浴期间以及水平位固定期间。淋巴细胞的输出量超过单核细胞和红细胞的输出量。除插管后立即发现外，未检测到粒细胞。夜间休息及水平位保持24小时期间细胞输出量较低。采取直立位后，淋巴细胞输出量增加约80倍，红细胞输出量增加40倍，这可能是由于休息期间组织中积聚的细胞被冲刷出来。在测力计骑行和静脉淤滞期间，细胞输出量增加，在该实验后的1小时休息期内增加得更多。静脉淤滞期间输出量下降，但淤滞解除后增加。淋巴细胞、红细胞和单核细胞输出量的变化模式相同。这表明输出量的波动取决于组织中血流的变化。加热期间及之后细胞的输出量似乎还取决于细胞毛细血管通透性的增加，因为红细胞的输出量超过了淋巴细胞的输出量。血液中红细胞/淋巴细胞比例高而淋巴液中该比例低，表明这两种细胞类型通过不同机制穿过毛细血管壁。
