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儿童和青少年颅内肿瘤的磁共振成像

Magnetic resonance imaging of intracranial tumors in children and adolescents.

作者信息

Peterman S B, Steiner R E, Bydder G M

出版信息

AJNR Am J Neuroradiol. 1984 Nov-Dec;5(6):703-9.

PMID:6093488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8333655/
Abstract

Magnetic resonance (MR) scans were reviewed of 25 children and adolescents from the age of 9 months to 18 years referred with a suspected or proven diagnosis of intracranial tumor. Twenty-one of these children had MR scans positive for tumor. Histology was available in 14. The other seven patients were managed clinically as cases of cerebral tumor, although histologic confirmation was lacking. Seventeen tumors displayed an increase in both T1 and T2. One dermoid tumor and part of another displayed a very short T1 (less than that of white matter). Two hamartomas had T1s similar to that of gray matter and a small increase in T2. Four of the children did not show MR or computed tomographic (CT) evidence of intracranial tumors. Follow-up of these cases for 1-23 months after the MR and CT studies revealed no subsequent clinical evidence of tumor. MR scans showed more extensive abnormality than did third-generation CT scans in eight of 10 cases and more extensive abnormality than EMI CT 1010 scans in 10 of 11 cases. Mass effects were better demonstrated in 14 of the 16 patients in whom they were seen. CT demonstrated calcification better than did MR in all four cases in which it was identified. The tumor-edema interface was shown better on CT in each of the three cases with contrast enhancement on CT. MR is a sensitive method of evaluating intracranial tumors in children and adolescents.

摘要

对25名年龄从9个月至18岁、因疑似或确诊颅内肿瘤而转诊的儿童和青少年进行了磁共振(MR)扫描。其中21名儿童的MR扫描显示肿瘤呈阳性。14名患者有组织学检查结果。另外7名患者虽缺乏组织学确诊,但临床上按脑肿瘤病例处理。17个肿瘤在T1和T2加权像上均显示信号增强。1个皮样囊肿和另1个皮样囊肿的部分区域T1加权像上信号极短(短于白质)。2个错构瘤T1加权像上信号与灰质相似,T2加权像上信号略有增强。4名儿童未显示颅内肿瘤的MR或计算机断层扫描(CT)证据。对这些病例在MR和CT检查后进行1至23个月的随访,未发现随后有肿瘤的临床证据。在10例中有8例MR扫描显示的异常范围比第三代CT扫描更广泛,在11例中有10例MR扫描显示的异常范围比EMI CT 1010扫描更广泛。在16例显示有占位效应的患者中,有14例的占位效应在MR上显示得更好。在所有4例发现有钙化的病例中,CT显示钙化比MR更好。在3例CT有强化的病例中,肿瘤-水肿界面在CT上显示得更好。MR是评估儿童和青少年颅内肿瘤的一种敏感方法。

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