Tracy P T, Hanigan W C, Kalyan-Raman U P
Childs Nerv Syst. 1986;2(6):297-300. doi: 10.1007/BF00271942.
The radiological and pathological findings in three children with pineocytomas are described. The patients presented with symptoms and signs of increased intracranial pressure. CT scans demonstrated obstructive hydrocephalus, but failed to visualize pineal masses that were subsequently seen on MR scans. A suboccipital, supracerebellar approach was used to obtain tissue for histological diagnosis and, in one case, achieve a total removal. Light microscopy demonstrated typical pineocytomatous rosettes without evidence of gangliocytic or astrocytic differentiation. Electron microscopy revealed numerous dense core vesicles with synaptic ribbons, suggesting neurosecretory capability. These three cases demonstrate the diagnostic advantage of MR imaging for tumors in the pineal region as well as the relatively well-differentiated histopathological characteristics of pineocytomas.
本文描述了3例松果体细胞瘤患儿的影像学和病理学表现。这些患者表现出颅内压升高的症状和体征。CT扫描显示梗阻性脑积水，但未能显示松果体肿块，而随后的磁共振成像（MR）扫描发现了这些肿块。采用枕下小脑上入路获取组织进行组织学诊断，其中1例实现了全切。光镜检查显示典型的松果体细胞瘤菊形团，未见神经节细胞或星形细胞分化迹象。电镜检查发现大量含突触带的致密核心囊泡，提示具有神经分泌功能。这3例病例显示了MR成像对松果体区肿瘤的诊断优势以及松果体细胞瘤相对良好的组织病理学分化特征。
