Machinami R, Adachi S
Pathol Res Pract. 1984 Sep;179(1):1-6. doi: 10.1016/S0344-0338(84)80053-9.
A case of glomus tumor was studied by light and electron microscopic enzyme histochemistry. Histologically, this case was classified as glomangioma or vascular form of glomus tumor. The tumor cells had ultrastructural characteristics of smooth muscle cells such as large amount of thin filaments with dense bodies, basal lamina and numerous pinocytotic vesicles. Among the 3 membrane associated enzymes, namely alkaline phosphatase, adenosine triphosphatase (ATPase) and 5'nucleotidase, only ATPase was detectable in the cell membrane and pinocytotic vesicles. It is suggested that the ATPase activity of the tumor cells shows additional evidence of smooth muscle character of glomus tumor.
通过光镜和电镜酶组织化学对1例血管球瘤进行了研究。组织学上，该病例被归类为血管球血管瘤或血管型血管球瘤。肿瘤细胞具有平滑肌细胞的超微结构特征，如大量含致密小体的细肌丝、基膜和众多吞饮小泡。在3种膜相关酶，即碱性磷酸酶、三磷酸腺苷酶（ATP酶）和5'-核苷酸酶中，仅在细胞膜和吞饮小泡中检测到ATP酶。提示肿瘤细胞的ATP酶活性为血管球瘤的平滑肌特征提供了额外证据。
