Rainey M, Ettedgui E, Pohl B, Balon R, Weinberg P, Yelonek S, Berchou R
Psychopathology. 1984;17 Suppl 3:40-51. doi: 10.1159/000284130.
To learn the effect of isoproterenol on patients meeting Research Diagnostic Criteria (RDC) for panic disorder, we administered isoproterenol, racemic sodium lactate, and glucose to them and to nonpsychiatric control subjects. Each subject received all 3 infusions, double-blind in random order. A 21-item self-rating panic scale was constructed from the RDC for panic disorder and was used to identify RDC panic attacks. The results of this study and the preliminary results from the infusions after treatment with imipramine are discussed in the text, and the results from the first patient to be reinfused after treatment are presented graphically.
为了解异丙肾上腺素对符合惊恐障碍研究诊断标准（RDC）患者的影响，我们对这些患者以及非精神科对照受试者给予了异丙肾上腺素、消旋乳酸钠和葡萄糖。每位受试者均接受了这3种输注，采用随机顺序进行双盲试验。根据惊恐障碍的RDC构建了一个包含21个项目的自评惊恐量表，用于识别符合RDC的惊恐发作。本文讨论了本研究的结果以及丙咪嗪治疗后输注的初步结果，并以图表形式展示了治疗后首次再次输注的第一位患者的结果。
