Penta-acetyl-gitoxin: the prototype of a prodrug in the cardiac glycoside series.
作者信息
Megges R, Portius H J, Repke K R
出版信息
Pharmazie. 1977 Nov;32(11):665-7.
PMID:609583
Abstract
Penta-acetyl-gitoxin is a suitable prodrug of gitoxin since it shows--side-effect latentiation, due to its inactive application form;--bioavailability, due to its improved solubility and thus good enteral absorption and--bioactivation, due to rapid de-acetylation in the body after absorption.
摘要
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