Fries W
J Comp Neurol. 1984 Nov 20;230(1):55-76. doi: 10.1002/cne.902300106.
The topical and laminar distribution of corticotectal cells, as well as their size and morphology, were studied in the macaque monkey with the horseradish peroxidase (HRP) technique. After HRP injections restricted primarily to the superficial layers of the colliculus, labelled cells were found in visual cortex (areas 17, 18, and 19) and both in the frontal eye field (area 8) and the adjacent part of premotor cortex (area 6). The clustering of labelled cells in visual cortex indicated that each of the anatomically and functionally distinct visual areas has its own set of collicular projections. When intermediate and deeper layers of the colliculus were injected, labelled cells were found also in posterior parietal cortex (area 7) where they were concentrated mainly on the posterior bank of the intraparietal fissure, in inferotemporal cortex (areas 20 and 21), in auditory cortex (area 22), in the somatosensory representation SII (anterior bank of sylvian fissure, area 2), in upper insular cortex (area 14), in motor cortex (area 4), in premotor cortex (area 6), and in prefrontal cortex (area 9). In the motor and premotor cortex, labelled cells formed a continuous band which appeared to stretch across finger-hand-arm-shoulder-neck representation. Similarly, the cluster of labelled cells in area 2 may correspond to the finger-hand representation of SII. The cortical regions not containing labelled cells were the somatosensory representation SI (areas 3, 1 and 2) and the infraorbital cortex. Labelled cells were restricted to layer V of all cortical areas except in the primary visual cortex, where labelled cells were found in both layer V and layer VI. The size spectrum of corticotectal cells ranged from 14.8 micron (average diameter) in area 17 to 27.8 micron in area 6, comprising cells as small as 8 micron and as large as 45 micron. Labelled cells in posterior parietal (area 7), in auditory (area 22), and in motor cortex (area 4) were small and distributed over only a narrow range of sizes. Those in premotor cortex (area 6) were often large and had a wide range in size distribution. The differences in size and morphology of corticotectal neurons suggest that they do not form a uniform class of neurons.
采用辣根过氧化物酶（HRP）技术，在猕猴身上研究了皮质顶盖细胞的局部和分层分布及其大小和形态。在主要将HRP注射到上丘表层后，在视觉皮层（17、18和19区）、额叶眼区（8区）以及运动前皮层相邻部分（6区）发现了标记细胞。视觉皮层中标记细胞的聚集表明，每个解剖学和功能上不同的视觉区域都有自己的一组上丘投射。当注射到上丘的中层和深层时，在顶叶后皮层（7区）也发现了标记细胞，它们主要集中在顶内沟的后壁，在颞下皮层（20和21区）、听觉皮层（22区）、体感代表区SII（外侧裂前壁，2区）、岛叶上部皮层（14区）、运动皮层（4区）、运动前皮层（6区）和前额叶皮层（9区）。在运动皮层和运动前皮层，标记细胞形成一条连续带，似乎横跨手指-手-臂-肩-颈代表区。同样，2区标记细胞的聚集可能对应于SII的手指-手代表区。不含标记细胞的皮质区域是体感代表区SI（3、1和2区）和眶下皮层。除初级视觉皮层外，标记细胞局限于所有皮质区域的V层，在初级视觉皮层中，V层和VI层都发现了标记细胞。皮质顶盖细胞的大小范围从17区的14.8微米（平均直径）到6区的27.8微米，包括小至8微米和大至45微米的细胞。顶叶后（7区）、听觉（22区）和运动皮层（4区）的标记细胞较小，且大小分布范围窄。运动前皮层（6区）的标记细胞通常较大，大小分布范围广。皮质顶盖神经元大小和形态的差异表明它们并非一类统一的神经元。
