Zhekov R, Kalaĭdzhiĭski A
Vet Med Nauki. 1977;14(10):78-84.
Investigations were carried out on the immunogenesis and the serum-protein profile in the treatment of broilers with the protein hydrolysate Hydroprot as well as with Newcastle disease vaccine. The treatment with Hydroprot led to a lower average geometric titer of antibodies--6.4 on the 14th, 6.9 on the 24th, and 6.6 on the 39th day following immunization. Characteristic changes in the serum-protein profile were established--decrease in the total serum-protein, increase in the globulins and particularly in the fractions the peak level of which corresponded to the period of most strongly expressed immunity. The results obtained were associated with the involvement of amino acid synthesis in the immunologic process. They showed that under the effect of the preparation applied there set in enhanced immunogenesis as an expression of changed immune responsiveness.
对用蛋白水解物Hydroprot以及新城疫疫苗治疗肉鸡的免疫发生和血清蛋白谱进行了研究。用Hydroprot治疗导致抗体平均几何滴度较低——免疫后第14天为6.4,第24天为6.9,第39天为6.6。确定了血清蛋白谱的特征性变化——血清总蛋白降低,球蛋白增加,尤其是其峰值水平与免疫表达最强时期相对应的组分增加。所获得的结果与氨基酸合成参与免疫过程有关。结果表明,在所应用制剂的作用下,免疫发生增强,这是免疫反应性改变的一种表现。