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[年龄指数与生存曲线的一种解释(作者译)]

[Age index and an interpretation of survivorship curves (author's transl)].

作者信息

Lohmann W

出版信息

Z Alternsforsch. 1977;32(5):461-6.

PMID:610074
Abstract

Clinical investigations showed that the age dependences of physiological functions do not show -- as generally assumed -- a linear increase with age, but an exponential one. Considering this result one can easily interpret the survivorship curve of a population (Gompertz plot). The only thing that is required is that the probability of death (death rate) is proportional to a function of ageing given by mu(t) = mu0 exp (alpha t). Considering survivorship curves resulting from annual death statistics and fitting them by suitable parameters, then the resulting alpha-values are in agreement with clinical data.

摘要

临床研究表明,生理功能的年龄依赖性并非如通常所认为的那样随年龄呈线性增加,而是呈指数增加。考虑到这一结果,人们可以很容易地解释种群的生存曲线(冈珀茨图)。唯一需要的是死亡概率(死亡率)与由μ(t) = μ0 exp(αt)给出的衰老函数成正比。考虑到由年度死亡统计数据得出的生存曲线并用合适的参数进行拟合,那么所得的α值与临床数据相符。

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