普萘洛尔——一种治疗门静脉高压症的药物？
Propranolol--a medical treatment for portal hypertension?
作者信息
Lebrec D, Nouel O, Corbic M, Benhamou J P
出版信息
Lancet. 1980 Jul 26;2(8187):180-2. doi: 10.1016/s0140-6736(80)90063-x.
PMID:6105342
Abstract
Continuous, oral administration of propranolol at doses which reduced the heart-rate by 25% produced a sustained decrease in portal venous pressure in cirrhotic patients with portal hypertension. This effect of propranolol might be useful in preventing recurrent bleeding due to ruptured oesophageal varices in patients with portal hypertension.
摘要
以能使心率降低25%的剂量持续口服普萘洛尔，可使门静脉高压的肝硬化患者门静脉压力持续下降。普萘洛尔的这一作用可能有助于预防门静脉高压患者因食管静脉曲张破裂导致的再出血。
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