Eberhard P, Mindt W
Biotelemetry. 1977;4(2):48-76.
Since the introduction of the technique of cutaneous1 pO2 measurement by directly heated oxygen sensors in 1972, the clinical applications and limitations of this new method have been extensively investigated. The method has proven to be of particular value in monitoring of high risk newborns as it affords the possibility of continuously monitoring clinically significant changes in the oxygenation state of the newborn. In this paper, methodological criteria for the assessment of the reliability of cutaneous pO2 monitoring are discussed. Particular consideration is given to the oxygen and temperature profiles in the vicinity of the skin sensor and to the response time of the sensor. In view of the fact that the cutaneous pO2 reflects the oxygen partial pressure at the level of arterialized cutaneous tissue, the method has limitations if it is used as an indirect determinant of arterial pO2.
自1972年采用直接加热式氧传感器测量皮肤pO₂技术以来,这种新方法的临床应用及局限性已得到广泛研究。事实证明,该方法在监测高危新生儿方面具有特殊价值,因为它能够持续监测新生儿氧合状态的临床显著变化。本文讨论了评估皮肤pO₂监测可靠性的方法学标准。特别考虑了皮肤传感器附近的氧和温度分布以及传感器的响应时间。鉴于皮肤pO₂反映的是动脉化皮肤组织水平的氧分压,若将其用作动脉pO₂的间接决定因素,该方法存在局限性。