Hongslo J K, Holland R I
Cell Biol Int Rep. 1977 Jul;1(4):369-74. doi: 10.1016/0309-1651(77)90067-4.
The established cell line LS (mouse fibroblasts) has been adapted to grow at otherwise toxic concentrations of fluoride. Different substrains of adapted LS cells consumed less glucose and converted less of the glucose to lactate than the unadapted cells. Differences were also found in the two parameters dependent on the number of generations grown in the presence of fluoride. The more generations with fluoride, the less lactate was produced and the less glucose consumed.
已建立的细胞系LS（小鼠成纤维细胞）已适应在原本有毒的氟化物浓度下生长。与未适应的细胞相比，适应后的LS细胞的不同亚系消耗的葡萄糖更少，将葡萄糖转化为乳酸的量也更少。在氟化物存在下生长的代数相关的两个参数中也发现了差异。氟化物存在的代数越多，产生的乳酸越少，消耗的葡萄糖也越少。
