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接受癸酸氟奋乃静治疗的患者出现“中暑”和/或“马利氏综合征”

["Heat stroke" and/or "Malin's syndrome" in a patient treated with fluphenazine decanoate].

作者信息

Ginestet D, Plumecoq C, Farine K, Brion S

出版信息

Encephale. 1977;3(4):327-31.

PMID:611015
Abstract

The role of the "heat stroke" is discussed on account of an observation of hyperthermia (42 degrees C or 107.6 Farenheit) that occured with a patient under fluphenazine decanoate, during the summer 1976 heat wave. Contrary to the American descriptions of heat strokes, the patient kept his perspiring ability. Moreover, there was no hypertonic extrapyramidal syndrome, but hypotonia instead. It is to be noted that the preliminary treatment by the corresponding standard neuroleptic (fluphenazine chlorhydrate) did not prevent that hyperthermia whose evolution was rapidly favorable.

摘要

鉴于1976年夏季热浪期间,一名接受癸酸氟哌啶醇治疗的患者出现体温过高(42摄氏度或107.6华氏度)的情况,本文对“中暑”的作用进行了讨论。与美国对中暑的描述相反,该患者仍保持出汗能力。此外,没有出现高渗性锥体外系综合征,而是出现了肌张力减退。需要注意的是,使用相应的标准抗精神病药物(盐酸氟奋乃静)进行初步治疗并未能预防体温过高的情况,但其病情发展迅速好转。

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