Sullivan C E, Issa F G, Berthon-Jones M, Eves L
Lancet. 1981 Apr 18;1(8225):862-5. doi: 10.1016/s0140-6736(81)92140-1.
Five patients with severe obstructive sleep apnoea were treated with continuous positive airway pressure (CPAP) applied via a comfortable nose mask through the nares. Low levels of pressure (range 4.5-10 cm H2O) completely prevented upper airway occlusion during sleep in each patient and allowed an entire night of uninterrupted sleep. Continuous positive airway pressure applied in this manner provides a pneumatic splint for the nasopharyngeal airway and is a safe, simple treatment for the obstructive sleep apnoea syndrome.
五名患有严重阻塞性睡眠呼吸暂停的患者通过舒适的鼻罩经鼻孔施加持续气道正压通气（CPAP）进行治疗。低水平压力（范围为4.5 - 10厘米水柱）完全防止了每位患者睡眠期间上气道阻塞，并实现了一整晚的不间断睡眠。以这种方式施加的持续气道正压通气为鼻咽气道提供了一个气动夹板，是阻塞性睡眠呼吸暂停综合征的一种安全、简单的治疗方法。
