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Inhibition of thromboxane synthetase does not necessarily prevent platelet aggregation.

作者信息

Bartele V, Cerletti C, Schiepatti A, di Minno G, de Gaetano G

出版信息

Lancet. 1981 May 9;1(8228):1057-8. doi: 10.1016/s0140-6736(81)92224-8.

DOI:10.1016/s0140-6736(81)92224-8
PMID:6112437
Abstract
摘要

相似文献

1
Inhibition of thromboxane synthetase does not necessarily prevent platelet aggregation.抑制血栓素合成酶不一定能防止血小板聚集。
Lancet. 1981 May 9;1(8228):1057-8. doi: 10.1016/s0140-6736(81)92224-8.
2
Thromboxane synthetase inhibition results in increased platelet sensitivity to prostacyclin.血栓素合成酶抑制会导致血小板对前列环素的敏感性增加。
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3
Different effects of thromboxane synthetase inhibitors on platelets from different individuals.
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4
Inhibition of platelet aggregation by 1-alkylimidazole derivatives, thromboxane A synthetase inhibitors.1-烷基咪唑衍生物（血栓素A合成酶抑制剂）对血小板聚集的抑制作用
Prostaglandins. 1981 Apr;21(4):543-54. doi: 10.1016/0090-6980(81)90003-4.
5
Thromboxane synthase inhibition in patients with atherosclerotic heart disease.
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6
Inhibition of arachidonate-induced human platelet aggregation by a single low oral dose of aspirin in combination with a thromboxane synthase inhibitor.
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7
Biology and biochemistry of thromboxane synthetase inhibitors.
Adv Prostaglandin Thromboxane Leukot Res. 1983;11:235-40.
8
UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity.UK-37,248，一种新型的选择性血栓素合成酶抑制剂，具有血小板抗聚集和抗血栓形成活性。
Thromb Res. 1981;23(1-2):145-62. doi: 10.1016/0049-3848(81)90247-4.
9
Thromboxane synthetase inhibitors as pharmacological tools: differential biochemical and biological effects on platelet suspensions.
Prostaglandins. 1977 Nov;14(5):897-907. doi: 10.1016/0090-6980(77)90306-9.
10
Platelet thromboxane synthetase inhibitors with low doses of aspirin: possible resolution of the "aspirin dilemma".低剂量阿司匹林联合血小板血栓素合成酶抑制剂：“阿司匹林困境”可能的解决办法
Science. 1983 Apr 29;220(4596):517-9. doi: 10.1126/science.6682245.

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Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease.了解前列腺素E2在健康和疾病状态下调节人类血小板活性中的作用。
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The antithrombotic profile of aspirin. Aspirin resistance, or simply failure?
阿司匹林的抗血栓形成特性。是阿司匹林抵抗，还是仅仅治疗失败？
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Immunology. 1996 Sep;89(1):158-64. doi: 10.1046/j.1365-2567.1996.d01-716.x.
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Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.肉桂亲和素的药理学特性研究，一种新型血栓素合酶和血栓素A2受体双重抑制剂。
Br J Pharmacol. 1994 Mar;111(3):906-12. doi: 10.1111/j.1476-5381.1994.tb14824.x.
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Novel antithrombotic drugs in development.正在研发的新型抗血栓药物。
Drugs. 1995 Jun;49(6):856-84. doi: 10.2165/00003495-199549060-00002.
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Antiplatelet drugs and thrombosis prevention: ticlopidine in perspective.抗血小板药物与血栓形成预防：噻氯匹定的前景展望
Agents Actions. 1984 Jan;14(1):109-12. doi: 10.1007/BF01966842.
8
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01).兔急性动脉血栓形成：盐酸达唑昔本（UK 37,248 - 01）治疗后血小板聚集减少
Br J Clin Pharmacol. 1983;15 Suppl 1(Suppl 1):49S-55S. doi: 10.1111/j.1365-2125.1983.tb02107.x.
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Human blood platelet behaviour after inhibition of thromboxane synthetase.血栓素合成酶抑制后人类血小板的行为
Br J Clin Pharmacol. 1983;15 Suppl 1(Suppl 1):31S-37S. doi: 10.1111/j.1365-2125.1983.tb02104.x.
10
Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour.血栓素合成酶抑制对花生四烯酸代谢及血小板行为的影响。
Br J Clin Pharmacol. 1983;15 Suppl 1(Suppl 1):23S-29S. doi: 10.1111/j.1365-2125.1983.tb02103.x.