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胃肠道淋巴瘤

Lymphomas of the gastrointestinal tract.

作者信息

Mcgovern V J

出版信息

Monogr Pathol. 1977(18):184-205.

PMID:611413
Abstract

Lymphomas occurring primarily in the alimentary tract present in the same way as carcinomas. Because they have a much better prognosis than carcinoma, especially in the case of gastrict lymphomas, it is important that they be diagnosed. For this reason, laparotomy if necessary should be undertaken in order to establish a histologic diagnosis of all alimentary neoplasms. With modern equipment, however, it is often possible to obtain enough tissue for diagnosis by endoscopic means. The ideal treatment is surgery, but if there is doubt about the completeness of excision or if there are involved lymphnodes, postoperative radiotherapy is desirable. The types of primary alimentary lymphoma are similar to those occurring in lymphnodes, and they may be follicular (nodular) or diffuse. Hodgkin's disease is less common than the other lymphomas and has a somewhat worse prognosis. The main prognostic features of alimentary lymphomas are type of lymphoma and degree of differentiation. Follicular lymphomas have a better prognosis than diffuse lymphomas and well differentiated lymphocytic lesions have a better prognosis than large cell poorly differentiated tumors. Lymphnode involvement has no significance in the overall survival rates.

摘要

主要发生于消化道的淋巴瘤,其临床表现与癌相同。由于它们的预后比癌好得多,尤其是胃淋巴瘤,因此进行诊断很重要。出于这个原因,如有必要应进行剖腹手术,以便对所有消化道肿瘤进行组织学诊断。然而,借助现代设备,通常可以通过内镜手段获取足够的组织用于诊断。理想的治疗方法是手术,但如果对切除的完整性存在疑问,或者存在受累淋巴结,则术后放疗是可取的。原发性消化道淋巴瘤的类型与发生于淋巴结的淋巴瘤相似,可为滤泡性(结节性)或弥漫性。霍奇金病比其他淋巴瘤少见,预后稍差。消化道淋巴瘤的主要预后特征是淋巴瘤类型和分化程度。滤泡性淋巴瘤的预后比弥漫性淋巴瘤好,高分化淋巴细胞性病变的预后比大细胞低分化肿瘤好。淋巴结受累对总生存率无影响。

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