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[口服百日咳疫苗的现状与未来]

[Present and future of oral pertussis vaccination].

作者信息

Falk W, Höfler K H, Rosanelli K, Kurz R

出版信息

Fortschr Med. 1981 Sep 10;99(34):1363-6.

PMID:6116657
Abstract

Parenteral immunization against whooping cough shows some disadvantages which led to proposals to curtail pertussis vaccination in some countries. As a result a striking rise in pertussis morbidity in these regions was noted, so vaccination against whooping cough is still indicated. We developed an oral vaccine for the neonate to achieve a protective immunity at a time when it is especially needed and to avoid side-reactions. Oral vaccine was given to more than 15,000 newborns, vaccination results of the last 3 years are reported.

摘要

针对百日咳的肠外免疫显示出一些缺点,这导致一些国家提出减少百日咳疫苗接种的建议。结果,这些地区百日咳发病率显著上升,因此百日咳疫苗接种仍然是必要的。我们开发了一种针对新生儿的口服疫苗,以便在特别需要的时候获得保护性免疫,并避免副作用。超过15000名新生儿接种了口服疫苗,本文报告了过去3年的接种结果。

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