Richardson M A, Craig T J
Am J Psychiatry. 1982 Mar;139(3):341-3. doi: 10.1176/ajp.139.3.341.
The authors used the Simpson-Angus Neurological Rating Scale and the Simpson Abbreviated Dyskinesia Rating Scale to evaluate 132 psychiatric inpatients for the presence of parkinsonism-like symptoms and tardive dyskinesia, respectively. Ninety-four percent of these patients had been on a stable drug regimen for a minimum of 2 weeks before assessment; 91% were being treated with neuroleptics, 42% with antiparkinson agents, and 7% with tricyclic antidepressants. Tardive dyskinesia and parkinsonism-like symptoms coexisted in 17.4% of the 132 patients. Such coexistence poses a therapeutic dilemma for the clinician because drug treatment of improve one neurological condition may exacerbate the other.
作者使用辛普森 - 安格斯神经评定量表和辛普森简易运动障碍评定量表，分别对132名精神科住院患者进行帕金森综合征样症状和迟发性运动障碍的评估。在评估前，这些患者中有94%已维持稳定的药物治疗方案至少2周；91%接受抗精神病药物治疗，42%接受抗帕金森药物治疗，7%接受三环类抗抑郁药治疗。在132名患者中，迟发性运动障碍和帕金森综合征样症状共存的情况占17.4%。这种共存给临床医生带来了治疗难题，因为改善一种神经状况的药物治疗可能会加重另一种状况。
