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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Thomson A B, Hotke C A, Weinstein W M

Comp Biochem Physiol A Comp Physiol. 1982;72(1):225-36. doi: 10.1016/0300-9629(82)90037-8.

The rate of in vitro uptake of glucose (gl), galactose (gal), 3-O-methyl glucose (MG), and fructose (fr) was determined using jejunal discs of hamster (ham), rat, rabbit (rab) and guinea pig (gp). 2. The maximal transport rates (Jdm) of each hexose were ham greater than rab greater than gp = rat; 3. The Michaelis constants were different for the four sugars; for gl the values were gp greater than rat greater than ham greater than rab. 4. The passive permeability coefficients (Pd) were similar for each sugar, and were greatest in ham and rat, and lowest in rat and gp. 5. The effective resistance of the intestinal unstirred water layer was lowest in ham and highest in gp and rat. 6. There were differences in the kinetic constants for gl estimated using discs and biopsies of jejunum, and the greater uptake into human biopsies than in the other species was due to the higher Jdm and Pd.

使用仓鼠、大鼠、兔子和豚鼠的空肠切片测定葡萄糖（gl）、半乳糖（gal）、3 - O - 甲基葡萄糖（MG）和果糖（fr）的体外摄取率。2. 每种己糖的最大转运速率（Jdm）为仓鼠大于兔子大于豚鼠 = 大鼠；3. 四种糖的米氏常数不同；对于葡萄糖，其值为豚鼠大于大鼠大于仓鼠大于兔子。4. 每种糖的被动渗透系数（Pd）相似，在仓鼠和大鼠中最大，在大鼠和豚鼠中最低。5. 肠道未搅动水层的有效阻力在仓鼠中最低，在豚鼠和大鼠中最高。6. 使用空肠切片和活检组织估计的葡萄糖动力学常数存在差异，人活检组织比其他物种摄取更多是由于更高的Jdm和Pd。

Thomson A B, Hotke C A, Weinstein W M

Comp Biochem Physiol A Comp Physiol. 1982;72(1):225-36. doi: 10.1016/0300-9629(82)90037-8.

The rate of in vitro uptake of glucose (gl), galactose (gal), 3-O-methyl glucose (MG), and fructose (fr) was determined using jejunal discs of hamster (ham), rat, rabbit (rab) and guinea pig (gp). 2. The maximal transport rates (Jdm) of each hexose were ham greater than rab greater than gp = rat; 3. The Michaelis constants were different for the four sugars; for gl the values were gp greater than rat greater than ham greater than rab. 4. The passive permeability coefficients (Pd) were similar for each sugar, and were greatest in ham and rat, and lowest in rat and gp. 5. The effective resistance of the intestinal unstirred water layer was lowest in ham and highest in gp and rat. 6. There were differences in the kinetic constants for gl estimated using discs and biopsies of jejunum, and the greater uptake into human biopsies than in the other species was due to the higher Jdm and Pd.

使用仓鼠、大鼠、兔子和豚鼠的空肠切片测定葡萄糖（gl）、半乳糖（gal）、3 - O - 甲基葡萄糖（MG）和果糖（fr）的体外摄取率。2. 每种己糖的最大转运速率（Jdm）为仓鼠大于兔子大于豚鼠 = 大鼠；3. 四种糖的米氏常数不同；对于葡萄糖，其值为豚鼠大于大鼠大于仓鼠大于兔子。4. 每种糖的被动渗透系数（Pd）相似，在仓鼠和大鼠中最大，在大鼠和豚鼠中最低。5. 肠道未搅动水层的有效阻力在仓鼠中最低，在豚鼠和大鼠中最高。6. 使用空肠切片和活检组织估计的葡萄糖动力学常数存在差异，人活检组织比其他物种摄取更多是由于更高的Jdm和Pd。