Ron M, Menashe M, Scherer D, Palti Z
Int J Gynaecol Obstet. 1982 Aug;20(4):301-5. doi: 10.1016/0020-7292(82)90059-5.
A deceleration response lasting up to 7 min was observed in 53 fetuses (out of 1910 studied) following the administration of 75 mg meperidine and 25 mg promethazine intravenously to the mothers during labor. Thirty-six of these fetuses reacted with baseline tachycardia following the deceleration with or without loss of baseline variability. Seven fetuses showed a variable deceleration pattern and six fetuses reacted with a late deceleration pattern following the first deceleration. Two newborns from the group showing a late deceleration pattern were delivered with an apgar score below 7 in 5 min. The probable mechanisms and significance of these changes are discussed.
在1910例研究胎儿中，有53例胎儿在分娩期间母亲静脉注射75毫克哌替啶和25毫克异丙嗪后出现了持续长达7分钟的减速反应。其中36例胎儿在减速后出现基线心动过速，伴或不伴有基线变异消失。7例胎儿表现为变异减速模式，6例胎儿在首次减速后出现晚期减速模式。在表现为晚期减速模式的组中有2例新生儿在5分钟时阿氏评分低于7分。讨论了这些变化的可能机制和意义。
