Wolfe M S, Calisher C H, McGuire K
Lancet. 1982 Dec 11;2(8311):1306-8. doi: 10.1016/s0140-6736(82)91511-2.
Spondweni virus is a mosquito-borne flavivirus previously reported to cause human disease in Southern and West Africa. A serologically confirmed case of Spondweni virus infection in a U.S. citizen residing in Upper Volta is reported. Symptoms included fever, chills, headache, myalgia, nausea, and rash. A greyish mucoid lining was present on the posterior pharynx. The differential diagnosis included rickettsial infection, leptospirosis, typhoid fever, and numerous viral illnesses including Lassa fever. Evidence of Spondweni virus infection was also found in two other U.S. citizens residing in Gabon and Cameroon. Spondweni virus might be a cause of acute febrile illness throughout West Africa, and its presence should be considered in the differential diagnosis of febrile illness and in antibody surveys in that region.
斯庞德温尼病毒是一种通过蚊子传播的黄病毒，此前有报道称其在南部和西非引发人类疾病。本文报告了一例血清学确诊的斯庞德温尼病毒感染病例，患者为居住在上沃尔特的一名美国公民。症状包括发热、寒战、头痛、肌痛、恶心和皮疹。后咽部可见灰白色黏液样黏膜。鉴别诊断包括立克次体感染、钩端螺旋体病、伤寒热以及包括拉沙热在内的多种病毒性疾病。在另外两名居住在加蓬和喀麦隆的美国公民中也发现了斯庞德温尼病毒感染的证据。斯庞德温尼病毒可能是西非急性发热性疾病的病因之一，在该地区的发热性疾病鉴别诊断和抗体调查中应考虑其存在。
