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东南亚各国产肠毒素大肠杆菌中定居因子(CFA/I、CFA/II和E8775)的出现情况。

The occurrence of colonisation factors (CFA/I, CFA/II and E8775) in enterotoxigenic Escherichia coli from various countries in South East Asia.

作者信息

Thomas L V, Rowe B

出版信息

Med Microbiol Immunol. 1982;171(2):85-90. doi: 10.1007/BF02124915.

DOI:10.1007/BF02124915
PMID:6128667
Abstract

Four hundred and fifty-eight enterotoxigenic strains of Escherichia coli (ETEC) were examined for the presence of colonisation factor antigens (CFA) I and II, and the putative colonisation factor, E8775, using an immunodiffusion technique with specific antisera. The ETEC strains had been isolated in Thailand, Bangladesh and from travellers returning to Japan from abroad. Approximately 14% of the ETEC strains possessed CFA/I and a further 13% of the strains possessed CFA/II. The E8775 antigen was found on 5% of the strains. CFA/I was found on strains of the serogroups 04, 015, 063, 078, 090, 0110, 0126, 0128, 0153, and 0? CFA/II was found on strains of the serogroups 06, 08, 09, 078, 0115, 0139, 0? and 0 rough. The E8775 antigen was found on strains of the serogroups 025, 0115, and 0167. The results of this study emphasise the need to continue the search for other mechanisms of adhesion used by ETEC strains, and in particular strains of the serogroups 027, 034, 0148 and 0166.

摘要

采用免疫扩散技术,使用特异性抗血清,对458株产肠毒素大肠杆菌(ETEC)进行检测,以确定其是否存在定居因子抗原(CFA)I和II以及假定的定居因子E8775。这些ETEC菌株是从泰国、孟加拉国以及从国外返回日本的旅行者中分离得到的。约14%的ETEC菌株携带CFA/I,另有13%的菌株携带CFA/II。5%的菌株发现有E8775抗原。在血清群04、015、063、078、090、0110、0126、0128、0153和0?的菌株中发现了CFA/I;在血清群06、08、09、078、0115、0139、0?和0粗糙型的菌株中发现了CFA/II。在血清群025、0115和0167的菌株中发现了E8775抗原。本研究结果强调,有必要继续寻找ETEC菌株,特别是血清群027、034、0148和0166的菌株所使用的其他黏附机制。

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