对无苯二氮䓬类药物尿液的偶然强化：一种药物滥用治疗干预措施的评估
Contingent reinforcement for benzodiazepine-free urines: evaluation of a drug abuse treatment intervention.
作者信息
Stitzer M L, Bigelow G E, Liebson I A, Hawthorne J W
出版信息
J Appl Behav Anal. 1982 Winter;15(4):493-503. doi: 10.1901/jaba.1982.15-493.
Abstract
This study evaluated contingent reinforcement for benzodiazepine-free urines as a therapeutic intervention for promoting reduced use of supplemental benzodiazepine drugs among methadone maintenance outpatients. Ten methadone maintenance patients were selected for participation on the basis of positive urinalysis results. During a 12-week intervention period these patients were offered clinic privileges, including monetary payments or methadone take-home doses, contingent on benzodiazepine negative urinalysis test results. Eight of ten participants responded to the intervention with at least 2.5 weeks of consecutive clean urines. An increase in benzodiazepine-negative tests during the contingent reinforcement period was significant for the group as a whole. The results suggest that more widespread application of contingent reinforcement procedures may be warranted in drug abuse treatment clinics.
摘要
本研究评估了以无苯二氮䓬尿液为条件的强化措施，作为一种治疗干预手段，以促进美沙酮维持治疗门诊患者减少补充苯二氮䓬类药物的使用。根据尿分析结果为阳性，选取了10名美沙酮维持治疗患者参与研究。在为期12周的干预期内，这些患者若尿分析苯二氮䓬检测结果为阴性，便可获得门诊特权，包括金钱奖励或美沙酮带回家剂量。10名参与者中有8人对干预措施有反应，至少连续2.5周尿液检测呈阴性。在整个强化期内，苯二氮䓬阴性检测结果有所增加，这对整个组来说具有显著性。结果表明，在药物滥用治疗诊所中，可能有必要更广泛地应用以条件为基础的强化程序。
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