Basu A, Chakrabarty K, Chatterjee G C
Toxicol Lett. 1982 Nov;14(1-2):21-5. doi: 10.1016/0378-4274(82)90005-4.
Acute intraperitoneal administration of lanthanum chloride to newborn chicks at the single dose of 250 mg/kg body weight inhibits calcium binding to brain synaptosomal membrane. There is also marked depression in the activities of neural Ca2+-ATPase, Mg2+-ATPase, and cholinesterase after acute lanthanum chloride intoxication. The inhibition of these enzymes in relation to depletion of calcium binding to the synaptosomal membrane has been discussed.
以250毫克/千克体重的单剂量向新生雏鸡急性腹腔注射氯化镧会抑制钙与脑突触体膜的结合。急性氯化镧中毒后,神经钙-ATP酶、镁-ATP酶和胆碱酯酶的活性也会显著降低。已经讨论了这些酶的抑制与突触体膜钙结合耗竭之间的关系。