• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Aromatic and benzylic hydroxyl substitution of imidazolines and phenethylamines: differences in activity at alpha-1 and alpha-2 adrenergic receptors.

作者信息

Ruffolo R R, Waddell J E

出版信息

J Pharmacol Exp Ther. 1983 Mar;224(3):559-66.

PMID:6131121
Abstract
摘要

相似文献

1
Aromatic and benzylic hydroxyl substitution of imidazolines and phenethylamines: differences in activity at alpha-1 and alpha-2 adrenergic receptors.咪唑啉和苯乙胺的芳族和苄基羟基取代：α-1和α-2肾上腺素能受体活性的差异。
J Pharmacol Exp Ther. 1983 Mar;224(3):559-66.
2
Receptor interactions of imidazolines. I. Affinity and efficacy for alpha adrenergic receptors in rat aorta.咪唑啉的受体相互作用。I. 对大鼠主动脉α肾上腺素能受体的亲和力和效能。
J Pharmacol Exp Ther. 1979 Jun;209(3):429-36.
3
Interaction of clonidine, its methylene-bridged analog, St 1913, and the benzylic hydroxyl-substituted derivative, St 1965, with alpha 1- and alpha 2-adrenoreceptors.可乐定、其亚甲基桥连类似物St 1913以及苄基羟基取代衍生物St 1965与α1和α2肾上腺素能受体的相互作用。
J Auton Pharmacol. 1983 Sep;3(3):185-93. doi: 10.1111/j.1474-8673.1983.tb00534.x.
4
The action and interaction of beta-phenethylamines and imidazolines on prejunctional alpha 2-adrenoceptors of guinea-pig ileum in the presence of the non-competitive antagonist benextramine.在非竞争性拮抗剂苄非他明存在的情况下，β-苯乙胺和咪唑啉对豚鼠回肠节前α2肾上腺素能受体的作用及相互作用。
J Pharm Pharmacol. 1984 Oct;36(10):668-72. doi: 10.1111/j.2042-7158.1984.tb04840.x.
5
Differences in the applicability of the easson-stedman hypothesis to the alpha 1- and alpha 2-adrenergic effects of phenethylamines and imidazolines.伊登-斯特德曼假说对苯乙胺类和咪唑啉类药物α1-和α2-肾上腺素能效应适用性的差异。
Eur J Pharmacol. 1983 Jan 21;86(3-4):471-5. doi: 10.1016/0014-2999(83)90199-1.
6
Receptor interactions of imidazolines. IV. Structural requirements for alpha adrenergic receptor occupation and receptor activation by clonidine and a series of structural analogs in rat aorta.咪唑啉的受体相互作用。IV. 可乐定及一系列结构类似物在大鼠主动脉中占据α肾上腺素能受体和激活受体的结构要求。
J Pharmacol Exp Ther. 1980 May;213(2):267-72.
7
Resolution and adrenergic activities of the optical isomers of 4-[1-(1-naphthyl)ethyl]-1H-imidazole.4-[1-(1-萘基)乙基]-1H-咪唑光学异构体的拆分及肾上腺素能活性
Chirality. 1992;4(7):432-8. doi: 10.1002/chir.530040706.
8
UK-14,304, a potent and selective alpha2-agonist for the characterisation of alpha-adrenoceptor subtypes.UK-14,304，一种用于鉴定α-肾上腺素能受体亚型的强效选择性α2-激动剂。
Eur J Pharmacol. 1981 Jul 10;72(4):413-5. doi: 10.1016/0014-2999(81)90588-4.
9
alpha-Adrenoceptors.α-肾上腺素能受体
Monogr Neural Sci. 1984;10:224-52.
10
Cyclohexylphenoxy amidoximes and imidazolines with antidepressive and alpha-adrenergic activity.具有抗抑郁和α-肾上腺素能活性的环己基苯氧基偕胺肟和咪唑啉。
Arzneimittelforschung. 1979;29(5):729-38.

引用本文的文献

1
Stachydrine, a Bioactive Equilibrist for Synephrine, Identified from Four Chinese Herbs.水黄皮中的育亨宾生物碱，一种从四种中国草药中分离得到的辛弗林等比活性物质
Molecules. 2023 Apr 29;28(9):3813. doi: 10.3390/molecules28093813.
2
α-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition.神经传递、突触可塑性和认知中的α-肾上腺素能受体
Front Pharmacol. 2020 Sep 29;11:581098. doi: 10.3389/fphar.2020.581098. eCollection 2020.
3
Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors.G蛋白偶联受体的激动剂结合、激动剂亲和力和激动剂效能
Br J Pharmacol. 2008 Apr;153(7):1353-63. doi: 10.1038/sj.bjp.0707672. Epub 2008 Jan 28.
4
Structure-function of alpha1-adrenergic receptors.α1肾上腺素能受体的结构与功能
Biochem Pharmacol. 2007 Apr 15;73(8):1051-62. doi: 10.1016/j.bcp.2006.09.010. Epub 2006 Sep 16.
5
Effects of alpha-2 adrenoceptor antagonists on rough-and-tumble play in juvenile rats: evidence for a site of action independent of non-adrenoceptor imidazoline binding sites.α-2肾上腺素能受体拮抗剂对幼年大鼠混战游戏的影响：作用位点独立于非肾上腺素能咪唑啉结合位点的证据
Psychopharmacology (Berl). 1994 Jan;113(3-4):493-9. doi: 10.1007/BF02245229.
6
Adrenoceptor-mediated effects of optically active catecholimidazolines in pithed rat.光学活性儿茶酚咪唑啉在去大脑大鼠中的肾上腺素能受体介导效应
Naunyn Schmiedebergs Arch Pharmacol. 1983 Jul;323(3):221-7. doi: 10.1007/BF00497667.
7
Interactions of MEN 935 (adimolol), a long acting beta- and alpha-adrenolytic antihypertensive agent, with postsynaptic alpha-adrenoceptors in different isolated blood vessels--influence of angiotensin II.长效β-和α-肾上腺素能阻断降压药MEN 935（阿地洛尔）与不同离体血管中突触后α-肾上腺素能受体的相互作用——血管紧张素II的影响
Naunyn Schmiedebergs Arch Pharmacol. 1986 Jul;333(3):277-83. doi: 10.1007/BF00512941.
8
Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors.章鱼胺和辛弗林立体异构体对α-肾上腺素能受体的作用。
Br J Pharmacol. 1988 Feb;93(2):417-29. doi: 10.1111/j.1476-5381.1988.tb11449.x.