十二指肠-胃反流的功能和形态学影响及其与消化性溃疡的关系。
The functional and morphological effects of duodeno-gastric reflux and their relation to peptic ulceration.
作者信息
Thomas W E
出版信息
Ann R Coll Surg Engl. 1983 Mar;65(2):112-6.
Abstract
The functional and morphological effects of duodeno-gastric reflux have been studied in the dog. Reflux causes hypersecretion of acid to pentagastrin and a hypergastrinaemic response to a standard meal, associated with antral gland hyperplasia. It is suggested that these changes are mediated by suppressed somatostatin activity, and that they may play an important part in the pathogenesis of peptic ulceration.
摘要
十二指肠-胃反流的功能和形态学效应已在犬身上进行了研究。反流导致对五肽胃泌素的胃酸分泌过多以及对标准餐的高胃泌素血症反应，并伴有胃窦腺增生。提示这些变化是由生长抑素活性受抑制介导的，且它们可能在消化性溃疡的发病机制中起重要作用。
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