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兔斯氏艾美耳球虫:化疗反应的证明

Eimeria stiedai in rabbits: the demonstration of responses to chemotherapy.

作者信息

Joyner L P, Catchpole J, Berrett S

出版信息

Res Vet Sci. 1983 Jan;34(1):64-7.

PMID:6132429
Abstract

The activity of sulphaquinoxaline, robenidine, methyl benzoquate, clopidol and a mixture of methyl benzoquate and clopidol (Lerbek; Dow), was studied in rabbits infected with hepatic coccidiosis due to Eimeria stiedai. Growth inhibition, oocyst production and the activity in the serum of glutamate dehydrogenase and gamma glutamyltransferase were studied as indicators of parasite development. Only sulphaquinoxaline and Lerbek gave satisfactory control of this parasite. The latter formulation was more effective than either of its constituents used alone.

摘要

对磺胺喹恶啉、罗苯尼丁、甲基苄喹酯、氯羟吡啶以及甲基苄喹酯与氯羟吡啶的混合物(Lerbek;陶氏化学公司产品)在感染斯氏艾美耳球虫所致肝球虫病的家兔体内的活性进行了研究。以生长抑制、卵囊产生以及血清中谷氨酸脱氢酶和γ-谷氨酰转移酶的活性作为寄生虫发育的指标进行了研究。只有磺胺喹恶啉和Lerbek对这种寄生虫有满意的控制效果。后一种制剂比其单独使用的任何一种成分都更有效。

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