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智障患者中抗帕金森病药物的突然停用。

The abrupt withdrawal of antiparkinsonian drugs in mentally handicapped patients.

作者信息

Carter G

出版信息

Br J Psychiatry. 1983 Feb;142:166-8. doi: 10.1192/bjp.142.2.166.

DOI:10.1192/bjp.142.2.166
PMID:6132644
Abstract

Long-term antiparkinsonian medication given to 20 mentally handicapped patients also on neuroleptics was abruptly withdrawn. Transient extrapyramidal signs developed in most patients during the following four weeks but in 60 per cent had disappeared by 12 weeks. Reintroduction of medication was necessary in only three patients, who developed acute dystonic reactions within one week of withdrawal.

摘要

给20名同时服用抗精神病药物的智力障碍帕金森病患者长期服用的抗帕金森病药物突然停药。在接下来的四周内,大多数患者出现了短暂的锥体外系症状,但60%的患者在12周时症状消失。只有三名患者在停药一周内出现急性肌张力障碍反应,因此需要重新用药。

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