智障患者中抗帕金森病药物的突然停用。
The abrupt withdrawal of antiparkinsonian drugs in mentally handicapped patients.
作者信息
Carter G
出版信息
Br J Psychiatry. 1983 Feb;142:166-8. doi: 10.1192/bjp.142.2.166.
PMID:6132644
Abstract
Long-term antiparkinsonian medication given to 20 mentally handicapped patients also on neuroleptics was abruptly withdrawn. Transient extrapyramidal signs developed in most patients during the following four weeks but in 60 per cent had disappeared by 12 weeks. Reintroduction of medication was necessary in only three patients, who developed acute dystonic reactions within one week of withdrawal.
摘要
给20名同时服用抗精神病药物的智力障碍帕金森病患者长期服用的抗帕金森病药物突然停药。在接下来的四周内，大多数患者出现了短暂的锥体外系症状，但60%的患者在12周时症状消失。只有三名患者在停药一周内出现急性肌张力障碍反应，因此需要重新用药。
相似文献
1
The abrupt withdrawal of antiparkinsonian drugs in mentally handicapped patients.智障患者中抗帕金森病药物的突然停用。
Br J Psychiatry. 1983 Feb;142:166-8. doi: 10.1192/bjp.142.2.166.
2
Tardive dyskinesia and other drug-induced movement disorders among handicapped children and youth.残疾儿童和青少年中的迟发性运动障碍及其他药物引起的运动障碍。
Appl Res Ment Retard. 1980;1(1-2):55-69. doi: 10.1016/0270-3092(80)90016-8.
3
Tardive dyskinesia in young mentally retarded individuals.年轻智障个体中的迟发性运动障碍
Arch Gen Psychiatry. 1986 Apr;43(4):335-40. doi: 10.1001/archpsyc.1986.01800040045007.
4
Antiparkinsonian drugs in the treatment of neuroleptic-induced extrapyramidal symptoms.
Can J Psychiatry. 1994 Mar;39(2):74-84. doi: 10.1177/070674379403900203.
5
Changes in extrapyramidal symptoms following anticholinergic drug withdrawal.抗胆碱能药物撤药后锥体外系症状的变化。
Clin Neuropharmacol. 1983 Mar;6(1):55-61. doi: 10.1097/00002826-198303000-00006.
6
[Antiparkinson drugs in neuroleptic treatment: comparative study of progressive and abrupt withdrawal].
Encephale. 1995 May-Jun;21(3):209-15.
7
Involuntary orofacial movements in hospitalised patients with mental handicap or epilepsy: relationship to developmental/intellectual deficit and presence or absence of long-term exposure to neuroleptics.患有智力障碍或癫痫的住院患者的不自主口面部运动：与发育/智力缺陷以及是否长期接触抗精神病药物的关系。
J Neurol Neurosurg Psychiatry. 1988 Jun;51(6):863-5. doi: 10.1136/jnnp.51.6.863.
8
[Complications of drug withdrawal from antiparkinson agents and neuroleptics].
Therapie. 1984 Jul-Aug;39(4):421-5.
9
Tardive dyskinesia and other clinical consequences of neuroleptic treatment in children and adolescents.迟发性运动障碍及儿童和青少年使用抗精神病药物治疗的其他临床后果。
Am J Psychiatry. 1984 Jan;141(1):20-3. doi: 10.1176/ajp.141.1.20.
10
Neuroleptic malignant syndrome-like state following a withdrawal of antiparkinsonian drugs.停用抗帕金森病药物后出现的类神经安定剂恶性综合征状态。
J Nerv Ment Dis. 1981 May;169(5):324-7. doi: 10.1097/00005053-198105000-00011.
Zotero 插件