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虎纹钝口螈(虎螈)和斑泥螈组织中一元胺氧化酶活性的分布情况。

Distribution of monoamine oxidase activity in tissues of the urodeles Ambystoma tigrinum (tiger salamander) and Necturus maculosus (mudpuppy).

作者信息

Hall T R, Urueña G

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983;74(1):35-9. doi: 10.1016/0742-8413(83)90144-5.

DOI:10.1016/0742-8413(83)90144-5
PMID:6132771
Abstract
  1. Monoamine oxidase (MAO) activity was determined fluorometrically in tissues of adult mudpuppies, and pre- (young) and post- (adult) metamorphic tiger salamanders. 2. From responses to specific inhibitors it was determined that 95% activity was MAO type A in all tissues. 3. In young salamanders MAO activity was greater in brain and intestine of males than of females, and was considerably higher in kidney of both sexes and in intestine of males compared to adults. 4. MAO activity was distributed differently in the mudpuppy compared to the salamander. Intestine and liver contained high activity and brain had relatively little MAO activity compared to salamander. 5. The apparent Michaelis constant of MAO activity in the different groups and tissues was generally similar, suggesting a similarity of the MAO molecule.
摘要
  1. 采用荧光法测定了成年泥螈以及幼体(幼年)和变态后(成年)的虎螈组织中的单胺氧化酶(MAO)活性。2. 根据对特异性抑制剂的反应确定,所有组织中95%的活性为A型MAO。3. 在幼年蝾螈中,雄性大脑和肠道中的MAO活性高于雌性,与成年蝾螈相比,两性肾脏和雄性肠道中的MAO活性要高得多。4. 与蝾螈相比,泥螈中MAO活性的分布有所不同。与蝾螈相比,肠道和肝脏含有高活性,而大脑中的MAO活性相对较低。5. 不同组和组织中MAO活性的表观米氏常数总体相似,表明MAO分子具有相似性。

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Distribution of monoamine oxidase activity in tissues of the urodeles Ambystoma tigrinum (tiger salamander) and Necturus maculosus (mudpuppy).虎纹钝口螈(虎螈)和斑泥螈组织中一元胺氧化酶活性的分布情况。
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983;74(1):35-9. doi: 10.1016/0742-8413(83)90144-5.
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