Gillespie W A, Simpson R A, Jones J E, Nashef L, Teasdale C, Speller D C
Lancet. 1983 May 7;1(8332):1037-9. doi: 10.1016/s0140-6736(83)92657-0.
The value of adding chlorhexidine to urine drainage bags of male patients treated with indwelling catheters after prostatectomy and other transurethral operations was assessed in a randomised, prospective, controlled was assessed in a randomised, prospective, controlled study. Chlorhexidine kept the contents of all drainage bags sterile, but the frequency of urinary infection in the chlordexidine group (51%) did not differ significantly from that in the control group (45%). Most infections were endogenous, caused by organisms which probably came from the patient's own urethra. It was concluded that the method has no value in urology units where standards of catheter care and closed drainage are properly maintained. Controlled studies in other types of catheterised patients are needed, especially when the risks of cross-infection are high.
在一项随机、前瞻性对照研究中，评估了在前列腺切除术后及其他经尿道手术后留置导尿管的男性患者尿液引流袋中添加洗必泰的价值。洗必泰可使所有引流袋内的内容物保持无菌，但洗必泰组的尿路感染发生率（51%）与对照组（45%）相比无显著差异。大多数感染是内源性的，由可能来自患者自身尿道的微生物引起。得出的结论是，在正确维持导尿管护理和密闭引流标准的泌尿外科病房，该方法没有价值。需要对其他类型的导尿患者进行对照研究，尤其是在交叉感染风险较高时。
