神经毒素对橙色螺旋体趋化性的抑制作用。
Inhibition of Spirochaeta aurantia chemotaxis by neurotoxins.
作者信息
Goulbourne E A, Greenberg E P
出版信息
J Bacteriol. 1983 Sep;155(3):1443-5. doi: 10.1128/jb.155.3.1443-1445.1983.
Abstract
The effects of neurotoxic compounds on the chemotactic response of Spirochaeta aurantia were investigated. In the presence of neurotoxins that affect action potential generation and transmission in excitable eucaryotic cells, D-xylose taxis was inhibited by 69 to 93%. Inhibition of chemotaxis was not due to decreased viability or motility. This study supports the hypothesis that the molecular basis for sensory signal transduction in S. aurantia involves ion fluxes across the cytoplasmic membrane.
摘要
研究了神经毒性化合物对橙色螺旋体趋化反应的影响。在影响可兴奋真核细胞动作电位产生和传导的神经毒素存在的情况下，D-木糖趋化性受到69%至93%的抑制。趋化性的抑制并非由于活力或运动性降低。本研究支持以下假设：橙色螺旋体感觉信号转导的分子基础涉及跨细胞质膜的离子通量。
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本文引用的文献
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J Bacteriol. 1981 Dec;148(3):837-44. doi: 10.1128/jb.148.3.837-844.1981.
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J Bacteriol. 1983 Feb;153(2):916-20. doi: 10.1128/jb.153.2.916-920.1983.
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