Fosnaugh K, Greenberg E P
Department of Microbiology, New York State College of Agriculture and Life Sciences, Cornell University, Ithaca 14853.
J Bacteriol. 1988 Apr;170(4):1768-74. doi: 10.1128/jb.170.4.1768-1774.1988.
A computer program has been designed to study behavior in populations of Spirochaeta aurantia cells, and this program has been used to analyze changes in behavior in response to chemoattractants. Three kinds of behavior were distinguished: smooth swimming, flexing, and reversals in direction of swimming after a short pause (120 ms). Cell populations exposed to chemoattractants spent, on average, 66, 33, and 1% of the time in these modes, respectively. After the addition of a chemoattractant, behavior was modified transiently--smooth swimming increased, flexing decreased, and reversals were suppressed. After addition of D-xylose (final concentration, 10 mM), the adaptation time (the time required for the populations to return to the unmodified behavior) for S. aurantia was 1.5 to 2.0 min. A model to explain the behavior of S. aurantia and the response of cells to chemoattractants is described. This model includes a coordinating mechanism for flagellar motor operation and a motor switch synchronizing device.
已设计出一个计算机程序来研究橙色螺旋体细胞群体的行为，该程序已用于分析细胞对化学引诱剂作出反应时行为的变化。区分出了三种行为：平稳游动、弯曲以及短暂停顿（120毫秒）后游动方向的反转。暴露于化学引诱剂的细胞群体在这些模式下平均分别花费66%、33%和1%的时间。添加化学引诱剂后，行为会短暂改变——平稳游动增加，弯曲减少，反转受到抑制。添加D-木糖（终浓度为10 mM）后，橙色螺旋体的适应时间（群体恢复到未改变行为所需的时间）为1.5至2.0分钟。描述了一个解释橙色螺旋体行为以及细胞对化学引诱剂反应的模型。该模型包括鞭毛马达操作的协调机制和马达开关同步装置。
