Nouet J C, Michat L
Bull Assoc Anat (Nancy). 1977 Jun;61(173):243-58.
The mitotic activity in the adrenal cortex has been studied during a 24 hours-cycle in male rats that have been sacrificed by perfusion of fixative. A method of calculation of the thickness of the zona germinativa is proposed : it permits to compute mitotic densities in relation to surface, and mitotic index. Mitotic activity seems to be the combination of a relatively low and constant activity occurring from 7 a.m. (local time) to 11 p.m., and an hyperactivity from 0 to 6 a.m. Two maxima are demonstrated : one at 0 h, and another one, more important, at 5 a.m. (local time). Results are analyzed, discussed and compared with others obtained on different organs : each tissue seems to have its own characteristics according to horary and intensity in mitotic activity.
通过灌注固定剂处死雄性大鼠后，研究了其肾上腺皮质在24小时周期内的有丝分裂活性。提出了一种计算生发层厚度的方法：该方法可计算相对于表面积的有丝分裂密度和有丝分裂指数。有丝分裂活性似乎是由上午7点（当地时间）至晚上11点相对较低且恒定的活性与凌晨0点至6点的活动亢进所组成。有两个峰值：一个在0点，另一个更明显的在上午5点（当地时间）。对结果进行了分析、讨论，并与在不同器官上获得的其他结果进行了比较：每个组织在有丝分裂活性的时间和强度方面似乎都有其自身特点。
